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Anti-PD-1 & TIGIT Reference Antibody (Rilvegostomig Biosimilar) (BIO0966SM)  
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100ug/詢價
1mg/詢價
5mg/詢價
大包裝/詢價

產(chǎn)品編號 BIO0966SM
英文名稱 Anti-PD-1 & TIGIT Reference Antibody (Rilvegostomig Biosimilar)
別    名 PDCD1 / PD-1 / CD279 & TIGIT / VSIG9 / VSTM3; Rilvegostomig  
抗體來源
克隆類型 Monoclonal
交叉反應 Human
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 146.06kDa
性    狀 Lyophilized
亞    型 IgG-like
純化方法 Protein A
緩 沖 液 100 mM Pro-Ac 20mM Arg pH 5.0
保存條件 -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹
產(chǎn)品圖片
To measure the binding ability of Rilvegostomig in Hu-PD1-his. Rilvegostomig bound to PD-1 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig 4, Rilvegostomig bound to HuPD-1-his, and the EC50 was 0.011 nM.
To measure the binding ability of Rilvegostomig in Human TIGIT-his. Rilvegostomig bound to TIGIT protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig 3, Rilvegostomig bound to Human TIGIT-his, and the EC50 was 0.040 nM.
The purity of Anti-PD-1 & TIGIT Reference Antibody (Rilvegostomig)is 95.78%, determined by SEC-HPLC.
Anti-PD-1 & TIGIT Reference Antibody (Rilvegostomig)on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The detected weight of Anti-PD-1 & TIGIT Reference Antibody (Rilvegostomig) is 145.78 kDa.
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