| 產(chǎn)品編號 | BIO0852SM |
| 英文名稱 | Anti-human GPC3 / Glypican-3 (Codrituzumab-MMAE Biosimilar) |
| 中文名稱 | |
| 抗體來源 | |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 150.85 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 亞 型 | Human IgG1 |
| 純化方法 | Protein A |
| 保存條件 | For long term storage, the produce should be stored at -20°C or lower. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
The killing ratio Codrituzumab-MMAE by HuH-7 increased with the increase of antibody concentration, and the killing Rate (%) reached 130% at antibody concentration of 40 nM.
Human GPC3 / Glypican-3 HEK293 Cell Line were stained Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab-MMAE) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.35 ug/mL.
MMAE is conjugated by sulfhydryl coupling,the DAR value of Anti TROP2 Reference Antibody (Sacituzumab govitecan) antibody is 3.8.
The purity of Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab-MMAE) is 99.73%, determined by SEC-HPLC.
Anti-GPC3 / Glypican-3 Reference Antibody (Codrituzumab-MMAE) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.
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