| 產(chǎn)品編號(hào) | bs-41408P |
| 英文名稱 | Recombinant SARS-Cov-2 N protein, N-His |
| 中文名稱 | 重組SARS冠狀病毒2核衣殼蛋白 |
| 別 名 | SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Prot 新冠病毒N蛋白; 新冠N蛋白; SARS-CoV-2 N蛋白; |
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Specific References (6) | bs-41408P has been referenced in 6 publications.
[IF=9.274] Purva Sharma. et al. COVID-19–Associated Kidney Injury: A Case Series of Kidney Biopsy Findings. J Am Soc Nephrol. 2020 Sep;31(9):1948-1958 IHC ; Human.
[IF=8.109] Romain Gasser. et al. Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2. Cell Rep. 2021 Mar;34:108790 other ;
[IF=8.008] Juanzu Liu. et al. Immunoprofiling of Severity and Stage of Bacterial Infectious Diseases by Ultrabright Fluorescent Nanosphere-Based Dyad Test Strips. ANAL CHEM. 2022;94(24):8818–8826 IA ; Human.
[IF=6.232] Shimaa Eissa. et al. Voltammetric-based immunosensor for the detection of SARS-CoV-2 nucleocapsid antigen. Microchim Acta. 2021 Jun;188(6):1-10 Other ;
[IF=3.306] Jia H. Ng. et al. Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19. Adv Chronic Kidney D. 2020 Sep;27:365 IHC ; Human.
[IF=2.089] Wei Ling Lau. et al. The COVID-Kidney Controversy: Can SARS-CoV-2 Cause Direct Renal Infection?. Nephron. ;:1-5 IHC ;
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| 理論分子量 | 46 kDa |
| 檢測(cè)分子量 | 50 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | SARS-Cov-2 |
| 序 列 | 1-419/419 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | E.coli |
| 活性 | Not tested |
| 標(biāo)簽 | N-His |
| 緩 沖 液 | PBS (pH7.4). |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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