| 產(chǎn)品編號(hào) | bsm-63210R |
| 英文名稱 | TTR/Prealbumin Recombinant Rabbit mAb |
| 中文名稱 | 轉(zhuǎn)甲狀腺素蛋白重組兔單抗 |
| 別 名 | Amyloid polyneuropathy; Amyloidosis I; ATTR; Carpal tunnel syndrome 1; CTS; CTS1; HsT2651; PALB; Prealbumin amyloidosis type I; Prealbumin. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 5G6 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 16 kDa |
| 檢測(cè)分子量 | 16 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Transthyretin |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Gene ID: 7276 轉(zhuǎn)甲狀腺素(transthyretin，TTR)蛋白由127個(gè)氨基酸組成，在生理?xiàng)l件下4個(gè)TTR蛋白單體分子結(jié)合一個(gè)T4單體分子形成聚合體，存在于血液中參與甲狀腺素的轉(zhuǎn)運(yùn)。TTR蛋白基因發(fā)生遺傳性突變以及在其他因素作用下TTR蛋白聚合體不穩(wěn)定，容易分離形成單體。立體結(jié)構(gòu)發(fā)生變化的TTR單體，進(jìn)一步重合形成蛋白纖維沉積于全身組織、臟器的細(xì)胞間質(zhì)，引起末梢神經(jīng)、自主神經(jīng)感覺(jué)障礙以及全身癥狀為特征的綜合臨床癥狀，稱為家族性多發(fā)性神經(jīng)性損害(familial amyloidotic polyneuropathy， |
