| 產(chǎn)品編號(hào) | D60240 |
| 英文名稱 | Lenalidomide(hemihydrate) |
| 中文名稱 | 來(lái)那度胺半水合物 |
| 克 隆 號(hào) | |
| CAS | 847871-99-2 |
| 理論分子量 | 268.27 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | -20℃ |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells |
