| 產(chǎn)品編號 | V6701 |
| 英文名稱 | TSH |
| 中文名稱 | 人促甲狀腺激素β亞基單克隆抗體 |
| 別 名 | TSHB_HUMAN; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta (TSH-B; TSH-beta); Thyrotropin beta chain; Thyrotropin alfa; TSH-β; |
| 克 隆 號 | 7H1 |
| 理論分子量 | 12kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Lyophilized or Liquid |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] Function: Indispensable for the control of thyroid structure and metabolism. Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. Similarity: Belongs to the glycoprotein hormones subunit beta family. SWISS: P01222 Gene ID: 7252 Database links: Entrez Gene: 7252 Human SwissProt: P01222 Human TSHB（甲狀腺刺激激素亞基Beta）是一種蛋白質(zhì)編碼基因。 與TSHB相關(guān)的疾病包括甲狀腺功能減退，先天性，非甲狀腺功能減退4和中樞性先天性甲狀腺功能減退。其相關(guān)途徑包括通過GPCR進(jìn)行信號傳遞和肽激素代謝。與該基因相關(guān)的基因本體論（GO）注釋包括激素活性。該基因的重要旁系同源物是FSHB。 |
