mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩中文字幕乱码在线视频,日韩精品高清在线视频,日韩商清av毛片网站
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
PINK1 Rabbit pAb (bs-22173R)  
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-22173R
英文名稱 PINK1 Rabbit pAb
中文名稱 絲氨酸/蘇氨酸蛋白激酶PINK1抗體
別    名 PINK1_HUMAN; PTEN Induced Putative Kinase 1; PTEN-Induced Putative Kinase Protein 1; BRPK; Serine/Threonine-Protein Kinase PINK1, Mitochondrial; Parkinson Disease(Autosomal Recessive) 6; Protein Kinase BRPK; EC 2.7.11.1; PARK6;  
Specific References  (1)     |     bs-22173R has been referenced in 1 publications.
[IF=4.109] Yihui Huo. et al. Exposure to copper activates mitophagy and endoplasmic reticulum stress-mediated apoptosis in chicken (Gallus gallus) cerebrum. ENVIRON TOXICOL. 2022 Nov;:  WB ;  Chicken.  
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 64 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PINK1: 441-540/581 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]

Function:
Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitement to dysfunctional mitochondria to initiate their degradation.

Subunit:
Interacts with PRKN. Interacts with FBXO7. Forms a complex with PRKN and PARK7 (PubMed:19229105).

Subcellular Location:
Mitochondrion outer membrane. Cytoplasm > cytosol.

Tissue Specificity:
Highly expressed in heart, skeletal muscle and testis, and at lower levels in brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine. Present in the embryonic testis from an early stage of development.

Post-translational modifications:
Autophosphorylated.

DISEASE:
Defects in PINK1 are the cause of Parkinson disease type 6 (PARK6) [MIM:605909]. A neurodegenerative disorder characterized by parkinsonian signs such as rigidity, resting tremor and bradykinesia. A subset of patients manifest additional symptoms including hyperreflexia, autonomic instability, dementia and psychiatric disturbances. Symptoms show diurnal fluctuation and can improve after sleep.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 protein kinase domain.

SWISS:
Q9BXM7

Gene ID:
65018

Database links:


產(chǎn)品圖片
Sample: Lane 1: Human HeLa cell lysates Lane 2: Human A431 cell lysates Lane 3: Human U-2OS cell lysates Primary: Anti- PINK1 (bs-22173R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 60 kDa
Sample: Lane 1: Mouse Muscle tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Heart tissue lysates Lane 4: Rat Muscle tissue lysates Lane 5: Rat Cerebrum tissue lysates Lane 6: Human U-2 OS cell lysates Primary: Anti-PINK1 (bs-22173R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 58 kDa
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
最新的精品亚洲一区二区| 一区二中文字幕在线看国产一区| 成人刺激性视频在线观看| 亚洲高清无遮挡在线观看| 久久久久精品无码专区喝奶| 正在播放 国产精品推荐| 精品人妻一区二区三区日产乱码| 淫荡淫水逼操烂视频| 日本入室强伦姧人妻中文| 日本乱人伦中文在线播放| 国产高清免费一级a久久| 人妻波多野结衣爽到喷水| 操的我的逼逼好爽好多水| 公交车上被后入搞逼漫画| 几巴怪物操逼视频| 国产精品久久大屁股白浆| 深插巴西美女的逼| 国产日韩精品v一区二区| 欧美日本大白屁股大黑逼操逼视频| 欧美尤物操逼毛茸茸真爽| 最新的亚洲欧美中文字幕| 男生和女人靠逼视频| 亚洲精品一区二区精华液| 冷色系的发色有哪些颜色| 欧美精品第一区二区三区| 国产精品自在自线。| 欧美一级特黄大片在线看| 国产精品视频一区二区三区分享| 啊啊不要你那痛死爽死了直播一区| 久久69精品久久久久免| 藏经阁91福利私人试看| 被大鸡巴操淫液视频| 精品麻豆国产免费一区二区三区| 国产中文字幕在线一区二区三区| 久操视频中文字幕在线观看| 欧美人与性动交b欧美精品| 国产一区二区三区在线观| 日本 日韩 欧美| 看一下日本人插逼逼洞视频| 综合伊人久久在一二三区| 黄色视频力肏女人|