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Rabbit Anti-MAGEA11  antibody (bs-22106R)  
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產品編號 bs-22106R
英文名稱 Rabbit Anti-MAGEA11  antibody
中文名稱 黑色素瘤相關抗原11抗體
別    名 Cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE 11; MAGE 11 antigen; MAGAB_HUMAN; MAGE11; MAGEA 11; Melanoma antigen family A 11; Melanoma associated antigen 11; MGC10511.  
研究領域 腫瘤  細胞生物  免疫學  染色質和核信號  信號轉導  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAGEA11 : 361-429/429 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 MAGEA11 (Melanoma antigen family A, 11) is a member of the MAGEA gene family. MAGEA proteins are expressed in melanomas and other cancers. MAGEA11 acts as androgen receptor co-regulator increasing androgen receptor activity by modulating the receptors interdomain interaction.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue.

Similarity:
Contains 1 MAGE domain.

SWISS:
P43364

Gene ID:
4110

Database links:
Entrez Gene: 4110 Human

Omim: 300344 Human

SwissProt: P43364 Human

Unigene: 670252 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (human laryngeal carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAGEA11) Polyclonal Antibody, Unconjugated (bs-22106R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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