mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
欧美日韩h片在线观看,亚洲V欧美V韩国V日本V
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-CD144/VE Cadherin  antibody (bs-22363R)  
~~~促銷(xiāo)代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@m.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-22363R
英文名稱(chēng) Rabbit Anti-CD144/VE Cadherin  antibody
中文名稱(chēng) 血管內(nèi)皮鈣粘蛋白抗體
別    名 VE-cadherin; 7B4 antigen; VECD; Vascular endothelial cell cadherin; 7B 4; 7B4; 7B4 antigen; Cadherin 5; Cadherin 5 type 2; Cadherin-5; Cadherin5; CD 144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Vascular endothelial cadherin; VE Cad antibody VEC; CADH5_HUMAN.  
Specific References  (1)     |     bs-22363R has been referenced in 1 publications.
[IF=4.932] Yi Ren. et al. Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway. Int Immunopharmacol. 2021 Nov;100:108077  WB ;  Mouse.  
研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  血管內(nèi)皮細(xì)胞  上皮細(xì)胞  內(nèi)皮細(xì)胞  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 86kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CD144/VE Cadherin: 46-140/784 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Subunit:
Interacts via cadherin 5 domain with PTPRB. Interacts with TRPC4. Interacts with KRIT1.

Subcellular Location:
Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.

Tissue Specificity:
Endothelial tissues and brain.

Post-translational modifications:
Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB.

Similarity:
Contains 5 cadherin domains.

SWISS:
P55284

Gene ID:
12562

Database links:
Entrez Gene: 1003 Human

Entrez Gene: 12562 Mouse

Entrez Gene: 307618 Rat

Omim: 601120 Human

SwissProt: P33151 Human

SwissProt: P55284 Mouse

Unigene: 76206 Human

Unigene: 21767 Mouse

Unigene: 224644 Rat



血管內(nèi)皮鈣粘蛋白(Vascularendothelial cell cadherin;VE-cadherin;VECD),又名CD144,Cadherin-5,是AJ連接(粘附連接)的主要粘附分子,是維持血管內(nèi)皮細(xì)胞極性和完整性必不可少的內(nèi)皮細(xì)胞特異性鈣粘蛋白.
產(chǎn)品圖片
Sample: Lane 1: MCF-7 (Human) Cell Lysate at 30 ug Lane 2: HUVEC (Human) Cell Lysate at 30 ug Lane 3: A431 (Human) Cell Lysate at 30 ug Lane 4: LOVO (Human) Cell Lysate at 30 ug Lane 5: SiHa (Human) Cell Lysate at 30 ug Primary: Anti-CD144/VE Cadherin (bs-22363R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human HUVEC cell lysates Lane 3: Human A431 cell lysates Lane 4: Human HeLa cell lysates Primary: Anti-CD144/VE Cadherin (bs-22363R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 86 kDa Observed band size: 140 kDa
Blank control:HUVC. Primary Antibody (green line): Rabbit Anti-CD144/VE Cadherin antibody (bs-22363R) Dilution: 1ug/Test; Secondary Antibody (white blue line) : Goat anti-rabbit IgG-AF488 Dilution: 0.5ug/Test. Isotype control(orange line):Normal Rabbit IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
Blank control:HUVEC. Primary Antibody (green line): Rabbit Anti-CD144/VE Cadherin antibody (bs-22363R) Dilution: 1ug/Test; Secondary Antibody (white blue line) : Goat anti-rabbit IgG-AF488 Dilution: 0.5ug/Test. Isotype control(orange line):Normal Rabbit IgG Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
一区二区久久久久久久久| 亚洲成人情色综合网| 中文字幕精品资源站| 欧洲在线观看亚洲三区| 精品久久久久久红码专区| 久久精品亚洲成在人线av| 国产日韩欧美制服另类| 欧美日韩激情精品久久久久久| 好看的福利电影在线| 色婷婷久久久久久久久久| 亚洲一区二区三区中文字幕一本| 欧美日韩国产成人精品自拍视频| 欧美日韩在线看免费看成人| 男人的天堂黄色大片| 国产在线一区二区三区欧美| 漫画韩漫画免费在线观看| 久久国产亚洲一区二区三区| 国产一级二级三级在线观看| 人妻少妇精品无码专区漫画| 九色精品国产亚洲av麻豆一| 国产线精品视频在线观看| 国产免费黄色片在线观看| 中文字幕久久中文字幕综合网| 国产精品日本一区二区在线看| 盗盗摄婷婷精品一区二区| 精品国产_亚洲人成在线| 国产精品午夜福利在线观看| 日韩精品欧美亚洲国产最大| 久草视频在线视频在线视频在线观看| 亚洲不卡一区二区三区在线| 国产视频网站在线不卡| 日本不卡久久伊人麻豆传媒| 色欲香天天综合免费区一区二| 国产永久免费观看的黄网站| 无码人妻视频一区二区三区| 亚洲AV综合色一区二区三区| 精品国产日本一区二区| 亚成区一区二区人妻熟女| 亚洲国产午夜精品不卡| 国产日韩欧美中文字幕在线| 亚洲欧美日韩在线三区|