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VMAT1 Rabbit pAb (bs-21800R)  
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產(chǎn)品編號(hào) bs-21800R
英文名稱 VMAT1 Rabbit pAb
中文名稱 嗜鉻顆粒胺轉(zhuǎn)運(yùn)蛋白VMAT1抗體
別    名 Adrenal chromaffin granule amine transporter; CGAT; CGAT; Chromaffin granule amine transporter; SLC18A1; Solute carrier family 18(vesicular monoamine), member 1; Solute carrier family 18 member 1; VAT 1; VAT1; Vesicular amine transporter 1; VMAT 1; VMAT1_  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse VMAT1 : 461-521/521 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008].

Function:
Involved in the vesicular transport of biogenic amines.

Subcellular Location:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Similarity:
Belongs to the major facilitator superfamily. Vesicular transporter family.

Database links:
Entrez Gene: 10493 Human

Entrez Gene: 26949 Mouse

Omim: 604631 Human

SwissProt: Q99536 Human

SwissProt: Q62465 Mouse

Unigene: 514199 Human

Unigene: 29210 Mouse



產(chǎn)品圖片
Sample: Eye (Mouse) Lysate at 40 ug Primary: Anti-VMAT1 (bs-21800R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-VMAT1 (bs-21800R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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