| 產(chǎn)品編號 | bs-23026R |
| 英文名稱 | CCR-2 Rabbit pAb |
| 中文名稱 | 細(xì)胞表面趨化因子受體2抗體 |
| 別 名 | C-C Chemokine receptor 2B; C C chemokine receptor type 2; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP 1 R; MCP1 RECEPTOR; MCP1R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor; CCR2_MOUSE; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R. |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞表面分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1ug/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCR-2: 301-373/373 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]. Function: Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Subunit: Binds to HIV-1 Tat. Interacts with ARRB1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Post-translational modifications: N-glycosylated. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P51683 Gene ID: 12772 Database links: Entrez Gene: 729230 Human Entrez Gene: 12772 Mouse Omim: 601267 Human SwissProt: P41597 Human SwissProt: P51683 Mouse Unigene: 511794 Human Unigene: 705362 Human Unigene: 6272 Mouse Unigene: 211983 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30
Blank control: Raw264.7.
Primary Antibody (green line): Rabbit Anti-CCR-2 antibody (bs-23026R)
Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody : Goat anti-rabbit IgG-AF647
Dilution: 1μg /test.
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