| 產(chǎn)品編號 | bs-20474R |
| 英文名稱 | HAVCR1 Rabbit pAb |
| 中文名稱 | 甲型肝炎病毒細(xì)胞受體1抗體 |
| 別 名 | HAVCR; HAVCR 1; HA; Vcr-1; hepatitis A virus cellular receptor 1; HKIM-1; Kidney Injury Molecule1; KIM1; KIM 1; KIM-1; TIM-1; TIMD 1; TIMD1; KM-1; TIMD1_MOUSe; T cell immunoglobin domain and mucin domain protein 1; T-cell immunoglobulin and mucin domain-c |
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Specific References (3) | bs-20474R has been referenced in 3 publications.
[IF=3.53] Yilan Shen et al. Interleukin-22 ameliorated acetaminophen-induced kidney injury by inhibiting mitochondrial dysfunction and inflammatory responses. Appl Microbiol Biotechnol. 2020 Jul;104(13):5889-5898. WB ; Mouse.
[IF=3.118] Qu S et al. The effects of resiquimod in an ovalbumin-induced allergic rhinitis model.Int Immunopharmacol. 2018 Jun;59:233-242. IF ; Mouse.
[IF=0] Ola-Davies OE et al. Ameliorative?effects?of?Annona?muricata?Linn. (Annonaceae)?against?potassium?dichromate-induced?hypertension?in?vivo:?involvement?of?Kim-1/p38?MAPK/Nrf2?signaling. J Basic Clin Physiol Pharmacol. 2019 May 3. IHC-P ; Rat.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 細(xì)菌及病毒 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,Flow-Cyt=1μg/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HAVCR1: 161-260/359 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] Function: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Subcellular Location: Membrane; Single-pass type I membrane protein (Probable). Tissue Specificity: Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. Similarity: Belongs to the immunoglobulin superfamily. TIM family. Contains 1 Ig-like V-type (immunoglobulin-like) SWISS: Q96D42 Gene ID: 26762 Database links: Entrez Gene: 26762 Human Omim: 606518 Human SwissProt: Q96D42 Human Unigene: 129711 Human |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human A549 cell lysates
Lane 2: Human HepG2 cell lysates
Lane 3: Human 293T cell lysates
Primary: Anti-HAVCR1 (bs-20474R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kDa
Observed band size: 55 kDa
Blank control (blue line):Hela(fixed with 70% ethanol (Overnight at 4℃) and then permeabilized with 90% ice-cold methanol for 30 min on ice).
Primary Antibody (green line): Rabbit Anti-HAVCR1/KIM1/TIM1 antibody(bs-20474R),
Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody (white blue line): Goat anti-rabbit IgG-FITC,Dilution: 1μg /test.
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