| 產(chǎn)品編號 | bs-12735R |
| 英文名稱 | Rabbit Anti-PLS1 antibody |
| 中文名稱 | 腸道特異性凝血酶PLS1抗體 |
| 別 名 | Fimbrin; I Fimbrin; I Plastin; Intestine specific plastin; Plastin 1(I isoform); Plastin 1; Plastin1. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PLS1: 41-140/329 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010] Function: Actin-bundling protein in the absence of calcium. Subcellular Location: Cytoplasm. Tissue Specificity: In small intestine, colon, and kidney; relatively lower levels of expression are detected in the lung and stomach. Post-translational modifications: Phosphorylated. Similarity: Contains 2 actin-binding domains. Contains 4 CH (calponin-homology) domains. Contains 2 EF-hand domains. SWISS: Q14651 Gene ID: 5357 Database links: Entrez Gene: 5357 Human Entrez Gene: 102502 Mouse Omim: 602734 Human SwissProt: Q14651 Human SwissProt: Q3V0K9 Mouse Unigene: 203637 Human |
