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Rabbit Anti-ROD1/PTBP3  antibody (bs-21038R)  
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產(chǎn)品編號(hào) bs-21038R
英文名稱 Rabbit Anti-ROD1/PTBP3  antibody
中文名稱 調(diào)節(jié)分化蛋白R(shí)OD1抗體
別    名 DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN.  
Specific References  (1)     |     bs-21038R has been referenced in 1 publications.
[IF=2.095] Zhou W et al. MiR-384 inhibits proliferation and migration of trophoblast cells via targeting PTBP3. Pregnancy Hypertens . 2020 Jul;21:132-138.  WB ;  Human.  
研究領(lǐng)域 細(xì)胞生物  結(jié)合蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse,Danio)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ROD1/PTBP3: 201-300/552 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Function:
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).

Subcellular Location:
Contains 4 RRM (RNA recognition motif) domains.

Tissue Specificity:
Expressed in several hematopoietic cell lines examined.

Similarity:
Contains 4 RRM (RNA recognition motif) domains.

SWISS:
O95758

Gene ID:
9991

Database links:

Entrez Gene: 9991 Human

Entrez Gene: 230257 Mouse

Entrez Gene: 83515 Rat

Omim: 607527 Human

SwissProt: O95758 Human

SwissProt: Q8BHD7 Mouse

SwissProt: Q9Z118 Rat

Unigene: 269988 Human

Unigene: 331640 Mouse

Unigene: 162818 Rat



產(chǎn)品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-ROD1/PTBP3 (bs-21038R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD
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