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Rabbit Anti-SGLT2  antibody (bs-20084R)  
~~~促銷代碼KT202411~~~
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200ul/2800.00元
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產(chǎn)品編號 bs-20084R
英文名稱 Rabbit Anti-SGLT2  antibody
中文名稱 鈉/葡萄糖協(xié)同轉運蛋白2抗體
別    名 Low affinity sodium glucose cotransporter; Low affinity sodium-glucose cotransporter; Na(+) glucose cotransporter 2; Na(+)/glucose cotransporter 2; OTTHUMP00000163298; SC5A2_HUMAN; SGLT 2; SLC5A 2; SLC5A2; Sodium glucose cotransporter 2; Sodium/glucose cotransporter 2; Solute carrier family 5 (sodium glucose cotransporter) member 2; Solute carrier family 5 (sodium/glucose transporter), member 2; Solute carrier family 5 member 2.  
Specific References  (2)     |     bs-20084R has been referenced in 2 publications.
[IF=2.59] Tian C et al. Short communication: A high-grain diet entails alteration in nutrient chemosensing of the rumen epithelium in goats. Animal Feed Science and Technology. Volume 262, April 2020, 114410.  IHC-P ;  
[IF=1.974] Changxin Tian. et al. The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet. ANIM SCI J. 2022 Jan;93(1):e13754  IHC ;  Goat.  
研究領域 腫瘤  細胞生物  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 73kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SGLT2: 351-450/672 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]

Function:
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

Subcellular Location:
Membrane.

DISEASE:
Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.

Similarity:
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

SWISS:
P31639

Gene ID:
6524

Database links:

Entrez Gene: 6524 Human

Entrez Gene: 399680 Cow

Entrez Gene: 492301 Dog

Entrez Gene: 246787 Mouse

Entrez Gene: 64522 Rat

Omim: 182381 Human

SwissProt: P31639 Human

SwissProt: Q923I7 Mouse

SwissProt: P26430 Rabbit

SwissProt: P53792 Rat

Unigene: 709195 Human

Unigene: 38870 Mouse

Unigene: 5887 Rat



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