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Rabbit Anti-PRKCBP1  antibody (bs-19178R)  
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產(chǎn)品編號 bs-19178R
英文名稱 Rabbit Anti-PRKCBP1  antibody
中文名稱 蛋白激酶C結(jié)合蛋白1抗體
別    名 ZMYND8; CTCL tumor antigen se14 3; Cutaneous T cell lymphoma associated antigen se14 3; KIAA1125; MGC31836; predicted protein of HQ2893; PRKCBP 1; PKCB1_HUMAN; PRO2893; Protein kinase C binding protein 1; Rack7; Zinc finger MYND domain containing protein 8; ZMYND 8.   
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  結(jié)合蛋白  淋巴細(xì)胞  t-淋巴細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rabbit,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 119kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRKCBP1: 1-100/1186 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Subunit:
Interacts in vitro with PRKCB1.

Subcellular Location:
Nuclear

Tissue Specificity:
Expressed in all tissues examined with highest expression in brain, lung, pancreas, and placenta. Expressed in cutaneous T-cell lymphomas (CTCL).

Similarity:
Contains 1 bromo domain.

SWISS:
Q9ULU4

Gene ID:
23613

Database links:

Entrez Gene: 23613 Human

SwissProt: Q9ULU4 Human

Unigene: 446240 Human



產(chǎn)品圖片
Sample: A549(Human) Cell Lysate at 40 ug Primary: Anti-PRKCBP1 (bs-19178R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 119 kD Observed band size: 119 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PRKCBP1) Polyclonal Antibody, Unconjugated (bs-19178R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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