產(chǎn)品編號(hào) | bs-18414R |
英文名稱(chēng) | Rabbit Anti-IL17RE antibody |
中文名稱(chēng) | 白細(xì)胞介素17受體E抗體 |
別 名 | FLJ23658; IL-17 receptor E; IL-17RE; interleukin 17 receptor E; Interleukin-17 receptor E; MGC71884; OTTHUMP00000158822; UNQ3056/PRO9877. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 72kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IL17RE: 201-300/667 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013] Function: Receptor which can activate the MAPK signaling pathway and seems to function at, or upstream of Ras. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors Subcellular Location: Membrane (isoform 1), Cytoplasm (isoforms 2 + 4), Secreted (isoforms 3 + 5) SWISS: Q8NFR9 Gene ID: 132014 Database links: Entrez Gene: 132014 Human SwissProt: Q8NFR9 Human Unigene: 208650 Human |