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Rabbit Anti-MON1A  antibody (bs-17711R)  
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產(chǎn)品編號 bs-17711R
英文名稱 Rabbit Anti-MON1A  antibody
中文名稱 MON1A蛋白抗體
別    名 FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A.  
研究領域 細胞生物  信號轉(zhuǎn)導  細胞凋亡  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Horse,Plants, Cynomolgus Monkey)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MON1A: 51-150/555 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 MON1A is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
Plays an important in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes.

Similarity:
Belongs to the MON1/SAND family.

SWISS:
Q86VX9

Gene ID:
84315

Database links:

Entrez Gene: 84315 Human

Entrez Gene: 72825 Mouse

Entrez Gene: 315999 Rat

Omim: 611464 Human

SwissProt: Q86VX9 Human

SwissProt: Q6PDG8 Mouse

Unigene: 655014 Human

Unigene: 38037 Mouse



產(chǎn)品圖片
Sample: Lane 1: 293T (Human) Cell Lysate at 30 ug Lane 2: Hela (Human) Cell Lysate at 30 ug Primary: Anti-MON1A (bs-17711R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70/55 kD Observed band size: 70/50 kD
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