| 產(chǎn)品編號(hào) | bs-16524R |
| 英文名稱 | Rabbit Anti-ZNF674 antibody |
| 中文名稱 | 鋅指蛋白674抗體 |
| 別 名 | MENTAL RETARDATION, X LINKED 92; MRX92; ZN674_HUMAN; Zinc finger family member 674; Zinc finger protein 674; ZNF673B. |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 67kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF674: 301-400/581 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010] Function: ZNF674 belongs to the krueppel C2H2-type zinc-finger protein family and contains 11 C2H2-type zinc fingers and 1 KRAB domain. ZNF674 may be involved in transcriptional regulation. Defects in ZNF674 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Subcellular Location: Nuclear Tissue Specificity: Expressed in testis. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 11 C2H2-type zinc fingers. Contains 1 KRAB domain. SWISS: Q2M3X9 Gene ID: 641339 Database links: Entrez Gene: 641339 Human Omim: 300573 Human SwissProt: Q2M3X9 Human |
| 產(chǎn)品圖片 |
Sample:
293T Cell (Human) Lysate at 40 ug
DU145 Cell (Human) Lysate at 40 ug
Primary: Anti-ZNF674 (bs-16524R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 67 kD
Observed band size: 67 kD
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