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Rabbit Anti-FLJ36733  antibody (bs-16128R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號 bs-16128R
英文名稱 Rabbit Anti-FLJ36733  antibody
中文名稱 CCDC44/卷曲螺旋結(jié)構(gòu)域蛋白44抗體
別    名 CCDC44; CDNA FLJ36733 fis; Coiled coil domain containing 44; Coiled-coil domain-containing protein 44; PRO0477; Taco1; TACO1_HUMAN; Translational activator of cytochrome c oxidase 1; Translational activator of mitochondrially-encoded cytochrome c oxidase I; UTERU2012856.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  線粒體  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLJ36733: 51-150/297 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]

Function:
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.

Subcellular Location:
Mitochondrion.

DISEASE:
Defects in TACO1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.

Similarity:
Belongs to the TACO1 family.

SWISS:
Q9BSH4

Gene ID:
51204

Database links:

Entrez Gene: 51204 Human

Omim: 612958 Human

SwissProt: Q9BSH4 Human

Unigene: 174134 Human



產(chǎn)品圖片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-FLJ36733 Polyclonal Antibody, Unconjugated(bs-16128R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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