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FLJ36733 Rabbit pAb (bs-16128R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-16128R
英文名稱 FLJ36733 Rabbit pAb
中文名稱 CCDC44/卷曲螺旋結構域蛋白44抗體
別    名 CCDC44; CDNA FLJ36733 fis; Coiled coil domain containing 44; Coiled-coil domain-containing protein 44; PRO0477; Taco1; TACO1_HUMAN; Translational activator of cytochrome c oxidase 1; Translational activator of mitochondrially-encoded cytochrome c oxidase I; UTERU2012856.  
研究領域 細胞生物  信號轉導  轉錄調節(jié)因子  線粒體  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測分子量
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLJ36733: 51-150/297 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]

Function:
Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.

Subcellular Location:
Mitochondrion.

DISEASE:
Defects in TACO1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.

Similarity:
Belongs to the TACO1 family.

SWISS:
Q9BSH4

Gene ID:
51204

Database links:

Entrez Gene: 51204 Human

Omim: 612958 Human

SwissProt: Q9BSH4 Human

Unigene: 174134 Human



產(chǎn)品圖片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat se
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