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Rabbit Anti-NCALD  antibody (bs-14442R)  
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說明書: 50ul  100ul  200ul
50ul/1180.00元
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200ul/2800.00元
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產(chǎn)品編號(hào) bs-14442R
英文名稱 Rabbit Anti-NCALD  antibody
中文名稱 神經(jīng)鈣蛋白NCALD抗體
別    名 MGC33870; MGC74858; NCALD; NCALD_HUMAN; Neurocalcin delta; Neurocalcin-delta.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  結(jié)合蛋白  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NCALD: 51-150/193 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Function:
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.

Tissue Specificity:
Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.

Similarity:
Belongs to the recoverin family.
Contains 4 EF-hand domains.

SWISS:
P61601

Gene ID:
83988

Database links:

Entrez Gene: 83988 Human

Entrez Gene: 281940 Cow

Entrez Gene: 52589 Mouse

Entrez Gene: 553106 Rat

Omim: 606722 Human

SwissProt: P61602 Cow

SwissProt: P61601 Human

SwissProt: Q91X97 Mouse

SwissProt: Q5PQN0 Rat

Unigene: 492427 Human

Unigene: 680132 Human

Unigene: 283370 Mouse

Unigene: 13744 Rat



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