| 產(chǎn)品編號 | bs-14413R |
| 英文名稱 | Rabbit Anti-DPCD antibody |
| 中文名稱 | 原發(fā)性纖毛運動障礙相關(guān)蛋白DPCD抗體 |
| 別 名 | Deleted in a mouse model of primary ciliary dyskinesia; DKFZp566F084; dpcd; DPCD protein; DPCD_HUMAN; OTTHUMP00000020329; Protein DPCD; RP11 529I10.4; RP11-529I10.4. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 細(xì)胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DPCD: 121-203/203 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DPCD is a 203 amino acid protein that is expressed at higher levels during ciliated cell differentiation, suggesting that DPCD plays a role in the function or formation of ciliated cells. In primary ciliary dyskinesia (PCD), an autosomal recessive disease that is caused by mutations affecting the proper function of cilia, an exon in the DPCD gene is deleted. The phenotype of PCD is variable, though it may include symptoms such as sinus inverse totalis, infertility or otitis media. In severe cases, patients develop end-stage bronchiectasis and require a lung transplantation. DPCD is highly expressed in testis, with weak expression in heart, pancreas and skeletal muscle. Function: May play a role in the formation or function of ciliated cells. Tissue Specificity: Highly expressed in the testis. Weakly expressed in pancreas, skeletal muscle and heart. Expression increases during ciliated cell differentiation. Similarity: Belongs to the DPCD family. SWISS: Q9BVM2 Gene ID: 25911 Database links: Entrez Gene: 25911 Human Entrez Gene: 226162 Mouse SwissProt: Q9BVM2 Human SwissProt: Q8BPA8 Mouse Unigene: 658128 Human Unigene: 21978 Mouse Unigene: 50057 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Human U87MG cell lysates
Primary: Anti-DPCD (bs-14413R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 23 kDa
Observed band size: 26 kDa
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