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Rabbit Anti-DDX49  antibody (bs-14330R)  
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產(chǎn)品編號 bs-14330R
英文名稱 Rabbit Anti-DDX49  antibody
中文名稱 ATP依賴RNA解旋酶DDX49抗體
別    名 DEAD(Asp Glu Ala Asp) box polypeptide 49; DEAD box protein 49; DDX49_HUMAN; FLJ10432; Probable ATP dependent RNA helicase DDX49; R27090 2.  
研究領域 細胞生物  發(fā)育生物學  轉(zhuǎn)錄調(diào)節(jié)因子  結合蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX49: 351-483/483 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX49 (DEAD-box protein 49) is a 483 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain. One of several members of the DEAD-box protein family, DDX49 may function as a an RNA helicase that is involved in pre-mRNA splicing events.

Function:
The function of DDX49 has not yet been determined.

Similarity:
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

SWISS:
Q9Y6V7

Gene ID:
54555

Database links:

Entrez Gene: 54555 Human

Entrez Gene: 234374 Mouse

Entrez Gene: 290660 Rat

SwissProt: Q9Y6V7 Human

SwissProt: Q3UTV0 Mouse

SwissProt: Q4FZF3 Mouse

Unigene: 143187 Human

Unigene: 388127 Mouse



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DDX49) Polyclonal Antibody, Unconjugated (bs-14330R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DDX49) Polyclonal Antibody, Unconjugated (bs-14330R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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