mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲成+人+综合+亚洲欧洲,喷水的视频一区二区三区
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Frizzled 10/CD350 Rabbit pAb (bs-13216R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@m.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-13216R
英文名稱(chēng) Frizzled 10/CD350 Rabbit pAb
中文名稱(chēng) CD350抗體
別    名 CD 350; CD 350 antigen; CD350; Frizzled(Drosophila) homolog 10; Frizzled-10; FZ 10; Fz-10; FZ10; FZD 10; FZD10; FZD10_HUMAN; FzE 7; FzE7; hFz 10; hFz10.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  G蛋白偶聯(lián)受體  細(xì)胞表面分子  表觀遺傳學(xué)  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 68 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Frizzled 10/CD350: 101-200/581 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins (FRPs) have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. Upregulation of frizzled-10 mRNA in human cells may lead to carcinogenesis through Wnt- Beta-catenin-TCF signaling pathway activation. Frizzled-10 has been found to be upregulated in HeLa S3, NT2, TMK1 and MKN74 cancer cell lines as well as in colorectal and breast cancer.

Function:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest levels in the placenta and fetal kidney, followed by fetal lung and brain. In adult brain, abundantly expressed in the cerebellum, followed by cerebral cortex, medulla and spinal cord; very low levels in total brain, frontal lobe, temporal lobe and putamen. Weak expression detected in adult brain, heart, lung, skeletal muscle, pancreas, spleen and prostate.

Post-translational modifications:
Ubiquitinated by ZNRF3, leading to its degradation by the proteasome.

Similarity:
Belongs to the G-protein coupled receptor Fz/Smo family.
Contains 1 FZ (frizzled) domain.

SWISS:
Q9ULW2

Gene ID:
11211

Database links:
UniProtKB/Swiss-Prot: Q9ULW2.1

產(chǎn)品圖片
Protein: embryo(mouse) lysates at 30ug; colon carcinoma(human) lysates at 30ug; Primary: Anti-Frizzled 10/CD350 (bs-13216R) at 1:200; Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000; ECL excitated the fluorescence; Predicted b
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goa
Tissue/cell: mouse placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal go
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat se
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
熟女菊蕾老妇俱乐部视频| 插欧美美女逼逼逼逼| 亚洲欧美一区二区爽爽爽| 大鸡吧老外操中国逼| 99久久久国产精品k影| 狂野国产性爱av| 亚洲 欧美 日韩 主播| 被下药强奷到舒服的视频| 哈啊慢点不要了视频| 粗大长内射女人视频| 韩美国男人叉女人| 欧美黄色三级成人小视频| 国产操小骚逼视频| 几巴怪物操逼视频| 欧美日韩国产这里只有精品| 欧美日韩国产这里只有精品| 亚洲国产精品伦理在线看| 欧美日韩久久久久久久久| 老司机午夜精品视频无码| 日韩有码视频在线| 美国大骚逼啊啊啊| 亚洲男性天堂一区二区三区| 市长含着秘书的奶头| 两个人免费视频高清| 国产一区二区三区免费观在线| 女人被男人躁爽色欲国产| 亚洲欧美国产原创一区二区三区| 天天日天天干天天天天操| 亚洲国产嫩草18久久久| 搬开女人下面使劲插视频| 欧美一区二区三区四公司| 男人的天堂日本在线观看| 日韩欧美一区二三区风间由美| 欧美办公室大鸡巴| 狠狠五月激情综合去干网| 亚洲福利小视频在线观看| 九九热在线精品免费看| 久久国产亚洲高清| 日本入室强伦姧人妻中文| 日韩有码一区二区三区在线观看| 大狼狗插阴道视频|