| 產(chǎn)品編號 | bs-13109R |
| 英文名稱 | ETEA Rabbit pAb |
| 中文名稱 | T細(xì)胞和嗜酸性粒細(xì)胞表達(dá)特應(yīng)性皮炎蛋白ETEA抗體 |
| 別 名 | AI462440; expressed in T cells and eosinophils in atopic dermatitis; faf2; FAF2_HUMAN; Fas associated factor family member 2; FAS-associated factor 2; KIAA0887; Protein ETEA; Protein expressed in T cells and eosinophils in atopic dermatitis; Protein expre |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 淋巴細(xì)胞 t-淋巴細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ETEA: 81-180/445 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ETEA is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of jAD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients. Function: May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. Subunit: Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1. Interacts with YOD1. Subcellular Location: Cytoplasm. Lipid droplet. Endoplasmic reticulum. Tissue Specificity: Broadly expressed, with highest levels in brain. Similarity: Contains 1 UBX domain. SWISS: Q96CS3 Gene ID: 23197 Database links: Entrez Gene: 23197 Human Entrez Gene: 76577 Mouse SwissProt: Q96CS3 Human SwissProt: Q3TDN2 Mouse |
| 產(chǎn)品圖片 |
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- ETEA (bs-13109R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
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