| 產(chǎn)品編號(hào) | bs-13023R |
| 英文名稱 | DNAJA2 Rabbit pAb |
| 中文名稱 | 細(xì)胞周期蛋白3抗體 |
| 別 名 | Cell cycle progression 3 protein; Cell cycle progression restoration gene 3 protein; CPR 3; CPR3; Dj3; DJA 2; DJA2; DnaJ(Hsp40) homolog subfamily A member 2; DNAJ; DnaJ homolog subfamily A member 2; DNAJA 2; Dnaja2; DNJ 3; Dnj3; DNJA2_HUMAN; HIRA interact |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse,Monkey) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAJA2: 151-250/412 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA2 (DnaJ homolog subfamily A member 2), also known as HIRA-interacting protein 4 or cell cycle progression restoration gene 3 protein, contains one CR-type zinc finger and is a co-chaperone of HSC 70. Function: Co-chaperone of Hsc70. Subcellular Location: Membrane. Similarity: Contains 1 CR-type zinc finger. Contains 1 J domain. SWISS: O60884 Gene ID: 10294 Database links: Entrez Gene: 10294 Human Entrez Gene: 56445 Mouse Omim: 611322 Human SwissProt: O60884 Human SwissProt: Q9QYJ0 Mouse Unigene: 368078 Human Unigene: 475573 Mouse Unigene: 3904 Rat |
