| 產(chǎn)品編號(hào) | bs-10050R |
| 英文名稱 | IBDV Rabbit pAb |
| 中文名稱 | 雞傳染性法氏囊病病毒(IBDV)抗體 |
| 別 名 | Infectious Bursal Disease Vaccine; Infectious bursal disease virus, IBDV; infectious bursal disease; IBD; Avian infectious bursal disease virus (IBDV) (Gumboro disease virus) |
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Specific References (1) | bs-10050R has been referenced in 1 publications.
[IF=2.243] Yina Ruanet al. T cell subset profile and inflammatory cytokine properties in the gut-associated lymphoid tissues of chickens during infectious bursal disease virus (IBDV) infection. Arch Virol
. 2020 Oct;165(10):2249-2258. IHC ; chicken.
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| 研究領(lǐng)域 | 免疫學(xué) 細(xì)菌及病毒 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Infectious Bursal Disease virus) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Infectious Bursal Disease Vaccine |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Infectious bursal disease (also known as IBD, Gumboro Disease, Infectious Bursitis and Infectious Avian Nephrosis) is a highly contagious disease of young chickens caused by infectious bursal disease virus (IBDV), characterized by immunosuppression and mortality generally at 3 to 6 weeks of age.
IBDV is a double stranded RNA virus that has a bi-segmented genome and belongs to the genus Avibirnavirus of family Birnaviridae. There are two distinct serotypes of the virus, but only serotype 1 viruses cause disease in poultry. At least six antigenic subtypes of IBDV serotype 1 have been identified by in vitro cross-neutralization assay. Viruses belonging to one of these antigenic subtypes are commonly known as variants, which were reported to break through high levels of maternal antibodies in commercial flocks, causing up to 60 to 100 percent mortality rates in chickens. With the advent of highly sensitive molecular techniques, such as reverse transcription polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP), it became possible to detect the vvIBDV, to differentiate IBDV strains, and to use such information in studying the molecular epidemiology of the virus. ????由雙鏈RNA病毒科的傳染性法氏囊病病毒(IBDV)所引起的一種雞的急性暴發(fā)性傳染病。表現(xiàn)為法氏囊淋巴組織和淋巴細(xì)胞壞死，發(fā)病率及死亡率均高。耐過(guò)雞的法氏囊組織受損，導(dǎo)致免疫抑制，影響其他疫苗的免疫效果，常造成免疫失敗。 ????IBDV的自然宿主僅為雛雞和火雞。從雞分離的IBDV只感染雞，感染火雞不發(fā)病，但能引起抗體產(chǎn)生。同樣，從火雞分離的病毒僅能使火雞感染，而不感染雞。不同品種的雞均有易感性。IBD母源抗體陰性的雞可于1周齡內(nèi)感染發(fā)病，有母源抗體的雞多在母源抗體下降至較低水平時(shí)感染發(fā)病。3～6周齡的雞最易感。也有15周齡以上雞發(fā)病的報(bào)道。該病全年均可發(fā)生，無(wú)明顯季節(jié)性。 ????病雞的糞便中含有大量病毒，病雞是主要傳染源。雞可通過(guò)直接接觸和污染了IBDV的飼料、飲水、墊料、塵埃、用具、車輛、人員、衣物等間接傳播，老鼠和甲蟲等也可間接傳播。有人從蚊子體內(nèi)分離出一株病毒，被認(rèn)為是一株IBDV自然弱毒，由此說(shuō)明媒介昆蟲可能參與該病的傳播。該病毒不僅可通過(guò)消化道和呼吸道感染，還可通過(guò)污染了病毒的蛋殼傳播，但未有證據(jù)表明經(jīng)卵傳播。另外，經(jīng)眼結(jié)膜也可傳播。 |
