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KCTD8 Rabbit pAb (bs-12087R)  
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產(chǎn)品編號(hào) bs-12087R
英文名稱 KCTD8 Rabbit pAb
中文名稱 鉀離子通道多聚體結(jié)構(gòu)域蛋白8抗體
別    名 BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8.  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Function:
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

Subunit:
Interacts as a tetramer with GABRB1 and GABRB2 (By similarity).

Subcellular Location:
Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.

Similarity:
Contains 1 BTB (POZ) domain.

SWISS:
Q6ZWB6

Gene ID:
386617

Database links:

Entrez Gene: 386617 Human

Entrez Gene: 243043 Mouse

SwissProt: Q6ZWB6 Human

SwissProt: Q50H33 Mouse

Unigene: 479644 Human

Unigene: 234821 Mouse



產(chǎn)品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Muscle tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Rat Cerebellum tissue lysates Lane 6: Rat Stomach tissue lysates Lane 7: Rat Muscle tissue lysates Primary: Anti-KCTD8 (bs-12087R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa
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