| 產(chǎn)品編號 | bs-11960R |
| 英文名稱 | SLITRK6 Rabbit pAb |
| 中文名稱 | 神經(jīng)突觸相關(guān)蛋白SLITRK6抗體 |
| 別 名 | 4832410J21Rik; MGC119595; MGC119596; MGC119597; OTTHUMP00000066012; SLIK6_HUMAN; SLIT and NTRK like family member 6; SLIT and NTRK like protein 6; SLIT and NTRK-like protein 6; Slit and trk like 6; Slit and trk like gene 6; SLITRK 6; Slitrk6. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 92 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLITRK6: 201-300/841 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK6 (SLIT and NTRK-like family, member 6) is an 841 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in select brain tissue, as well as in both adult and fetal lung, SLITRK6 functions to suppress neurite outgrowth, playing a role in the regulation of neuronal function. Multiple isoforms of SLITRK6 exist due to alternative splicing events. Function: Suppresses neurite outgrowth. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors. Similarity: Belongs to the SLITRK family. Contains 11 LRR (leucine-rich) repeats. Contains 2 LRRCT domains. Contains 2 LRRNT domains. SWISS: Q9H5Y7 Gene ID: 84189 Database links: Entrez Gene: 84189 Human Entrez Gene: 239250 Mouse Omim: 609681 Human SwissProt: Q9H5Y7 Human SwissProt: Q8C110 Mouse |
