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Rabbit Anti-SLC14A2  antibody (bs-11801R)  
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產(chǎn)品編號 bs-11801R
英文名稱 Rabbit Anti-SLC14A2  antibody
中文名稱 尿素轉(zhuǎn)運型糖蛋白A2抗體
別    名 UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14(urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6.  
Specific References  (1)     |     bs-11801R has been referenced in 1 publications.
[IF=2.976] Franziska J?ger. et al. Immunohistochemical detection of urea transporter-A in the tear-producing part of the lacrimal system. ANN ANAT. 2022 Oct;244:151991  IHC ;  Human, Mouse, Pig.  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 101 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC14A2/UT-A: 501-600/920 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.

Similarity:
Belongs to the urea transporter family.

SWISS:
Q15849

Gene ID:
8170

Database links:

Entrez Gene: 8170 Human

Entrez Gene: 27411 Mouse

Entrez Gene: 54302 Rat

Omim: 601611 Human

SwissProt: Q15849 Human

SwissProt: Q8R4T9 Mouse

SwissProt: Q62668 Rat

Unigene: 710927 Human

Unigene: 44158 Mouse

Unigene: 10157 Rat



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