產(chǎn)品編號(hào) | bs-11327R |
英文名稱 | Rabbit Anti-PTP zeta antibody |
中文名稱 | 磷酸蛋白聚糖PTPRZ抗體 |
別 名 | Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; protein tyrosine phosphatase receptor type Z1; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatase, receptor type, Z polypeptide 1; Protein tyrosine phosphatase, receptor type, zeta polypeptide 1; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPZ; R PTP zeta 2; R-PTP-zeta; Receptor type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta; RPTP-BETA; RPTPB; RPTPbeta; PTPRZ_HUMAN; PTPζ. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse (predicted: Rat) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 251kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PTP zeta: 421-520/2315 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] Function: May be involved in the regulation of specific developmental processes in the CNS. Subunit: The carbonic-anhydrase like domain binds to contactin (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. Contains 1 alpha-carbonic anhydrase domain. Contains 1 fibronectin type-III domain. Contains 2 tyrosine-protein phosphatase domains. SWISS: P23471 Gene ID: 5803 Database links: Entrez Gene: 5803 Human Entrez Gene: 19283 Mouse Omim: 176891 Human SwissProt: P23471 Human Unigene: 489824 Human Unigene: 10088 Rat |