| 產(chǎn)品編號(hào) | bs-4841R |
| 英文名稱 | Rabbit Anti-TACI antibody |
| 中文名稱 | 腫瘤壞死因子受體超家族成員13B抗體 |
| 別 名 | TACI; CD267; CD267 antigen; CVID; TNFRSF 13B; TNFRSF 14B;TNFRSF13B; TNFRSF13B protein; TNFRSF14B; Transmembrane activator and CAML interactor; Tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 淋巴細(xì)胞 t-淋巴細(xì)胞 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 32kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TNFRSF13B/CD267/TACI : 21-120/293 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17. Subcellular Location: Membrane; Single-pass type III membrane protein. Tissue Specificity: Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells. Similarity: Contains 2 TNFR-Cys repeats. SWISS: O14836 Gene ID: 23495 Database links: Entrez Gene: 23495 Human Entrez Gene: 57916 Mouse Omim: 604907 Human SwissProt: O14836 Human SwissProt: Q9ET35 Mouse Unigene: 158341 Human Unigene: 265915 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Stomach tissue lysates
Lane 2: Mouse Lung tissue lysates
Primary: Anti-TACI (bs-4841R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 30 kDa
Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- TACI (bs-4841R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 30 kD
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