| 產(chǎn)品編號(hào) | bs-11125R |
| 英文名稱 | ROM1 Rabbit pAb |
| 中文名稱 | 視網(wǎng)膜感光細(xì)胞外節(jié)膜蛋白1抗體 |
| 別 名 | Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Cat,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ROM1: 121-220/351 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008]. Function: May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Retina (photoreceptor). In rim region of ROS (rod outer segment) disks. DISEASE: Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2. Similarity: Belongs to the PRPH2/ROM1 family. SWISS: Q03395 Gene ID: 6094 Database links: Entrez Gene: 6094 Human Entrez Gene: 19881 Mouse Omim: 180721 Human SwissProt: Q03395 Human SwissProt: P32958 Mouse Unigene: 281564 Human |
