| 產(chǎn)品編號(hào) | bs-11121R |
| 英文名稱 | PCDHA7 Rabbit pAb |
| 中文名稱 | 原鈣粘附蛋白α7抗體 |
| 別 名 | CNRS4; PCDA7_HUMAN; PCDH alpha 7; PCDH-alpha-7; PCDHA7; Protocadherin alpha 7; Protocadherin alpha-7. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞骨架 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 98 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCDHA7: 601-700/937 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA7 (Protocadherin alpha-7) is a 937 amino acid single-pass transmembrane protein that contains six cadherin domains and functions as a potential calcium-dependent cell-adhesion protein, possibly playing a role in the creation and maintenance of neuronal connections. There are two isoforms of PCDHA7 that are produced as a result of alternative splicing events. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subunit: Contains 6 cadherin domains. Subcellular Location: Cell membrane. Similarity: Contains 6 cadherin domains. SWISS: Q9UN72 Gene ID: 56141 Database links: Entrez Gene: 56141 Human Omim: 606313 Human SwissProt: Q9UN72 Human Unigene: 199343 Human |
