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Rabbit Anti-GABA A Receptor alpha 3  antibody (bs-6500R)  
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產(chǎn)品編號 bs-6500R
英文名稱 Rabbit Anti-GABA A Receptor alpha 3  antibody
中文名稱 G氨基丁酸受體α3抗體
別    名 GABA(A) receptor subunit alpha 3; GABA(A) receptor subunit alpha-3; GABR A3; GABRA 3; GABRA-3; GABRA3; Gamma aminobutyric acid (GABA) A receptor alpha 3; Gamma aminobutyric acid A receptor alpha 3; Gamma aminobutyric acid receptor subunit alpha 3; gamma-aminobutyric acid A receptor alpha 3; Gamma-aminobutyric acid receptor subunit alpha-3; GBRA3_HUMAN.  GABA A Receptor α3; GABA A Receptor α 3; GABA A Receptor α-3; GABA A Receptor-α3;
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRA3: 101-200/492 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subunit:
Binds UBQLN1. Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Subcellular Location:
Cell junction; synapse; postsynaptic cell membrane; Cell membrane.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily.

SWISS:
P34903

Gene ID:
2556

Database links:

Entrez Gene: 282237 Cow

Entrez Gene: 492223 Dog

Entrez Gene: 2556 Human

Entrez Gene: 14396 Mouse

Entrez Gene: 24947 Rat

Omim: 305660 Human

SwissProt: P10064 Cow

SwissProt: P34903 Human

SwissProt: P26049 Mouse

SwissProt: P20236 Rat

Unigene: 123024 Human

Unigene: 102286 Mouse

Unigene: 447666 Mouse

Unigene: 10367 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GABA A Receptor alpha 3) Polyclonal Antibody, Unconjugated (bs-6500R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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