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KCNE1L Rabbit pAb (bs-9929R)  
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產(chǎn)品編號(hào) bs-9929R
英文名稱 KCNE1L Rabbit pAb
中文名稱 鉀離子通道蛋白家族成員1樣蛋白抗體
別    名 AMME syndrome candidate gene 2 protein; AMMECR2 protein; Cardiac voltage gated potassium channel accessory subunit 5; KCNE1 like; KCNE5; Mink; MinK like protein; Potassium voltage gated channel subfamily E member 1 like protein; Potassium voltage gated channel, Isk related family, member 1 like; Voltage gated potassium channel accessory subunit 5; KCE1L_HUMAN.  
研究領(lǐng)域 心血管  神經(jīng)生物學(xué)  通道蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow)
產(chǎn)品應(yīng)用 Flow-Cyt=1ug/test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE1L: 11-110/142 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 KCNE1L belongs to the potassium channel KCNE family which represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.

Subcellular Location:
Plasma membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta.

DISEASE:
Defects in KCNE1L are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR) [MIM:300194]. A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis.

Similarity:
Belongs to the potassium channel KCNE family.

SWISS:
Q9UJ90

Gene ID:
23630

Database links:

Entrez Gene: 23630 Human

Omim: 300328 Human

SwissProt: Q9UJ90 Human



產(chǎn)品圖片
Blank control: Hela. Primary Antibody (green line): Rabbit Anti-KCNE1L antibody (bs-9929R) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test. Protocol Th
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