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Cyclophilin 40/PPID Rabbit pAb (bs-9878R)  
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50ul/1180.00元
100ul/1980.00元
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產(chǎn)品編號 bs-9878R
英文名稱 Cyclophilin 40/PPID Rabbit pAb
中文名稱 親環(huán)蛋白(親環(huán)素)40抗體
別    名 40 kDa peptidyl prolyl cis trans isomerase; 40 kDa peptidyl prolyl cis trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin D; Cyclophilin D; Cyclophilin related protein; Cyclophilin-40; Cyclophilin-related protein; Cyclophilin40; CyclophilinD; CYP 40; CYP 40; CYP-40; CYP40; CYP40; CYPD; CYPD; MGC33096; Peptidyl Prolyl Isomerase D; Peptidyl Prolyl Isomerase D; Peptidyl-prolyl cis-trans isomerase D; Peptidylprolyl isomerase D; PPIase; PPIase D; PPID; PPID; PPID_HUMAN; Rotamase; Rotamase D.  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20, 40 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cyclophilin D: 281-370/370 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of cyclosporin A (CsA) and is encoded by a single unique gene conserved from yeast to humans. Cyclophilin B (CyPB) is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. Cyclophilin D (CyP40) is a widely expressed cytoplasmic protein that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It is a widely expressed cytoplasmic protein.

Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Subunit:
Binds ESR1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
Contains 1 PPIase cyclophilin-type domain.
Contains 3 TPR repeats.

SWISS:
Q08752

Gene ID:
5481

Database links:

Entrez Gene: 5481 Human

Entrez Gene: 67738 Mouse

Entrez Gene: 361967 Rat

Omim: 601753 Human

SwissProt: Q08752 Human

SwissProt: Q9CR16 Mouse

SwissProt: Q6DGG0 Rat

Unigene: 183958 Human

Unigene: 295252 Mouse

Unigene: 136915 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse NIH/3T3 cell lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Human HeLa cell lysates Lane 5: Human 293T cell lysates Lane 6: Human HepG2 cell lysates Lane 7: Human K562 cell lysates Lane 8: Human Jurkat cell lysates Primary: Anti-Cyclophilin 40/PPID (bs-9878R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20, 40 kDa Observed band size: 41 kDa
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