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Rabbit Anti-Proteasome 20S beta 6  antibody (bs-9358R)  
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50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-9358R
英文名稱 Rabbit Anti-Proteasome 20S beta 6  antibody
中文名稱 蛋白酶體PSMβ6抗體
別    名 Delta; LMPY; Macropain delta chain; MGC5169; Multicatalytic endopeptidase complex delta chain; Proteasome (prosome macropain) subunit beta type 6; Proteasome beta 6 subunit; Proteasome catalytic subunit 1; Proteasome delta chain; Proteasome subunit beta 6; Proteasome subunit beta type 6; Proteasome subunit beta type-6; Proteasome subunit delta; Proteasome subunit Y; PSB6_HUMAN; PSMB 6; PSMB6; PSY large multifunctional protease Y; Y antibody.  
研究領域 細胞生物  免疫學  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22kDa
細胞定位 細胞核 細胞漿 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Proteasome 20S beta 6: 21-120/239 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Subunit:
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. This subunit can be displaced by the equivalent immune-specific subunit PSMB9. Interacts with HIV-1 TAT protein.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the peptidase T1B family.

SWISS:
P28072

Gene ID:
5694

Database links:

Entrez Gene: 5694 Human

Entrez Gene: 19175 Mouse

Entrez Gene: 29666 Rat

Omim: 600307 Human

SwissProt: P28072 Human

SwissProt: Q60692 Mouse

SwissProt: P28073 Rat

Unigene: 77060 Human

Unigene: 98 Mouse

Unigene: 8118 Rat



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