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Rabbit Anti-GIMAP4  antibody (bs-8270R)  
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產品編號 bs-8270R
英文名稱 Rabbit Anti-GIMAP4  antibody
中文名稱 GTP酶IMAP家族成員4抗體
別    名 GTPase, IMAP family member 3 pseudogene; Ian4; Gimap5; 2010110D23Rik; GIMAP 3; GIMAP3; GTPase IMAP family member 3; GTPase of the immune associated protein 3; Immune associated nucleotide 4; Immunity associated nucleotide 4 protein; GIMA4_HUMAN.  
研究領域 細胞生物  免疫學  干細胞  t-淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GIMAP4: 21-120/329 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
Tissue specificity:
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.

Function:
May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.

Subcellular Location:
Cytoplasm, cytosol (By similarity).

Tissue Specificity:
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.

Post-translational modifications:
Phosphorylated at very low levels in resting splenocytes. Rapidly and transiently phosphorylated in response to splenocyte activation (By similarity).

Similarity:
Belongs to the IAN GTP-binding protein family.

SWISS:
Q9NUV9

Gene ID:
55303

Database links:

Entrez Gene: 55303 Human

Omim: 608087 Human

SwissProt: Q9NUV9 Human

Unigene: 647101 Human

Unigene: 648582 Human



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