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Rabbit Anti-MTFR1  antibody (bs-7632R)  
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產(chǎn)品編號(hào) bs-7632R
英文名稱 Rabbit Anti-MTFR1  antibody
中文名稱 線粒體裂變調(diào)節(jié)蛋白1抗體
別    名 MTFR 1; Chondrocyte protein with a poly proline region; Chondrocyte protein with a poly-proline region; CHPPR; FAM54A2; KIAA0009; Mitochondrial fission regulator 1; MTFR1_HUMAN.  
Specific References  (1)     |     bs-7632R has been referenced in 1 publications.
[IF=7.076] Dong Ma. et al. Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. Plos Biol. 2020 Aug;18(8):e3000808  WB,IF,IP ;  Mouse.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  線粒體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTFR1: 201-300/333 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.

Function:
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity).

Subcellular Location:
Mitochondrion (By similarity). Note=May be associated with the inner and the outer mitochondrial membrane (By similarity).

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the MTFR1/FAM54 family.

SWISS:
Q15390

Gene ID:
9650

Database links:
UniProtKB/Swiss-Prot: Q15390.2

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