mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
久热这里只有精品999,国产在线精品一区二区在,日韩精品一区二区三区av在线
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-Factor VIII  antibody (bs-2974R)  
~~~促銷(xiāo)代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@m.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-2974R
英文名稱(chēng) Rabbit Anti-Factor VIII  antibody
中文名稱(chēng) 凝血因子8/第八凝血因子/第八因子相關(guān)抗原抗體
別    名 coagulation factor VIII; Ahf; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII associated protein b; Coagulation factor VIII isoform b; Coagulation factor VIII procoagulent component; Coagulation factor VIIIc; Dna segment on chromosome x unique 1253 expressed sequence; Dxs1253e; F8; F8 protein; F8b; F8c; Factor VIII F8b; FactorVIII; FVIII; Hema coagulation factor VIIIc procoagulent component; Hemophilia a; Hemophilia classic; OTTHUMP00000061446; Procoagulant component; FⅧ-Ag; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; AHF; DXS1253E; F8B; F8C; FVIII; HEMA; FA8_HUMAN.  
Specific References  (7)     |     bs-2974R has been referenced in 7 publications.
[IF=5.818] Xiaoxiao Song. et al. Effects of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infection on the Surface Glycoprofiling of Porcine Pulmonary Microvascular Endothelial Cells. VIRUSES-BASEL. 2022 Nov;14(11):2569  IF ;  Pig.  
[IF=5.201] Qiong Li. et al. CD73+ Mesenchymal Stem Cells Ameliorate Myocardial Infarction by Promoting Angiogenesis. Front Cell Dev Biol. 2021; 9: 637239  WB,IHC ;  Rat.  
[IF=4.75] Zhao, Yuechao, et al. "Estrogen-Induced CCN1 is Critical for Establishment of Endometriosis-like Lesions in Mice." Molecular Endocrinology (2014).  IHC-P ;  Mouse.  
[IF=4.51] Ning et al. Calcyclin-binding protein inhibits proliferation, tumorigenicity, and invasion of gastric cancer. (2007) Mol.Cancer.Re. 5:1254-62  IHC-P ;  Mouse.  
[IF=2.81] Zhu et al. Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells. (2015) PLoS.On. 10:e0135866  IF(ICC) ;  Rat.  
[IF=1.92] Tang, Xi-lan, et al. "Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts." Inflammation: 1-8.  Rat.  
[IF=1.709] Nabeshima CK et al. Immunohistological study of the effect of vascular Endothelial Growth Factor on the angiogenesis of mature root canals in rat molars.J Appl Oral Sci. 2018;26:e20170437.  IHC ;  Rat.  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞表面分子  血管內(nèi)皮細(xì)胞  腫瘤細(xì)胞生物標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細(xì)胞定位 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Rabbit Factor VIII: 85-190/2351 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

Function:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Subunit:
Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.

Subcellular Location:
Secreted, extracellular space.

Post-translational modifications:
Sulfation on Tyr-1699 is essential for binding vWF.

DISEASE:
Hemophilia A (HEMA) [MIM:306700]: A disorder of blood coagulation characterized by a permanent tendency to hemorrhage. About 50% of patients have severe hemophilia resulting in frequent spontaneous bleeding into joints, muscles and internal organs. Less severe forms are characterized by bleeding after trauma or surgery. Note=The disease is caused by mutations affecting the gene represented in this entry. Of particular interest for the understanding of the function of F8 is the category of CRM (cross-reacting material) positive patients (approximately 5%) that have considerable amount of F8 in their plasma (at least 30% of normal), but the protein is non-functional; i.e. the F8 activity is much less than the plasma protein level. CRM-reduced is another category of patients in which the F8C antigen and activity are reduced to approximately the same level. Most mutations are CRM negative, and probably affect the folding and stability of the protein.

Similarity:
Belongs to the multicopper oxidase family.
Contains 3 F5/8 type A domains.
Contains 2 F5/8 type C domains.
Contains 6 plastocyanin-like domains.

SWISS:
P00451

Gene ID:
2157

Database links:

Entrez Gene: 403875 Dog

Entrez Gene: 2157 Human

Entrez Gene: 14069 Mouse

Entrez Gene: 397339 Pig

Omim: 300841 Human

SwissProt: O18806 Dog

SwissProt: P00451 Human

SwissProt: Q06194 Mouse

SwissProt: P12263 Pig

Unigene: 654450 Human

Unigene: 1805 Mouse



第VIII因子抗體用于血管源性良性和惡性腫瘤的診斷,也用于遺傳性血友病的研究。在正常動(dòng)脈、靜脈、毛細(xì)血管及心臟內(nèi)細(xì)胞的血管內(nèi)皮細(xì)胞上陽(yáng)性表達(dá)。第Ⅷ因子相關(guān)抗原抗體在巨核細(xì)胞及血小板上也有表達(dá)。 第Ⅷ因子相關(guān)抗原:是一種糖蛋白,廣泛存在于血管上皮、肝臟、脾竇上皮、及淋巴內(nèi)皮細(xì)胞,是血管內(nèi)皮細(xì)胞及其內(nèi)源性良惡性腫瘤的特異性標(biāo)記。主要用于血管原性良惡性腫瘤和血管肉瘤的診斷。少數(shù)副睪、子宮和輸卵管的腺癌樣瘤也有表達(dá).
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Factor VIII) Polyclonal Antibody, Unconjugated (bs-2974R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
美女草草影院在线观看视频| 欧美日韩永久精品一区二区| 9色国产精品一区粉嫩| 欧洲日韩在线观看一区二区三区视频| 在线播放亚洲欧美日韩| 国产精品美女作爱视频| 午夜影院网站免费观看| 欧美日韩在线免费视频| 国产精品亚洲一区二区三区欲| 日韩码一码二码三码区别| 人妻精品久久一区二区| 欧美老熟妇乱人伦人妻| 国产美女高潮抽搐流水在线看| 91午夜精品亚洲一区二区三区| 精品久久久久精品三级18| 欧美加勒比一区二区三区| 国产欧美一区二区综合日本| 中文字幕人妻乱一区二区三区| 最新中文乱码字字幕在线看| 婷婷激情亚洲综合综合久久| 欧美日韩永久精品一区二区| 成人一级片黄色一级片| 日韩一区二区人妻9999| 日本在线观看黄视频| 日本韩国亚洲欧美一区二区三区| 99亚洲视频一区二区| 最新99精品视频在线观看| 久久免费少妇高潮视频| 欧美日韩一区二区三区自拍| 日产国产精品久久久久久| 亚洲AV永久无码精品加勒比| 国产亚洲综合欧美一区| 国产精品亚洲А∨天堂网不卡| 亚洲精品国自产在线| 日本午夜免费福利视频| 一区二区不卡99精品日韩| 最新中文乱码字字幕在线看| 日韩码一码二码三码区别| 国产成人av一区二区三区在线观看| 91久久久久人妻精品专区| 欧美精品亚洲精品日|