| 產(chǎn)品編號 | bs-6264R |
| 英文名稱 | EMP2 Rabbit pAb |
| 中文名稱 | 上皮細(xì)胞膜蛋白2抗體 |
| 別 名 | EMP-2; EMP2; EMP2_HUMAN; Epithelial membrane protein 2; Protein XMP. |
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Specific References (2) | bs-6264R has been referenced in 2 publications.
[IF=7.273] Torella D et al. MicroRNA Regulation of the Hyper-Proliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes Mellitus.(2018) Diabetes. Sep 26 IF ; Rat.
[IF=3.117] Pan, Jian. et al. miR-340-5p mediates the therapeutic effect of mesenchymal stem cells on corneal neovascularization. 2021 Sep 08 WB ; human,rat.
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| 研究領(lǐng)域 | 腫瘤 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 細(xì)胞粘附分子 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 19/24 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EMP2: 65-167/167 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the PMP-22/EMP/MP20 family. SWISS: P54851 Gene ID: 2013 Database links: Entrez Gene: 2013 Human Entrez Gene: 13731 Mouse Omim: 602334 Human SwissProt: P54851 Human SwissProt: O88662 Mouse Unigene: 531561 Human Unigene: 246009 Mouse |
