| 產(chǎn)品編號 | bs-4088R |
| 英文名稱 | SLC27A5 Rabbit pAb |
| 中文名稱 | 脂肪酸轉(zhuǎn)運蛋白5抗體 |
| 別 名 | ACSB; ACSVL6; BA CoA ligase; BACS; BAL; Bile acid CoA ligase; Bile acyl CoA synthetase; Cholate CoA ligase; FACVL3; FATP 5; FATP5; Fatty acid Coenzyme A ligase very long chain 3; Fatty acid transport protein 5; Solute carrier family 27(fatty acid transpor |
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Specific References (2) | bs-4088R has been referenced in 2 publications.
[IF=5.201] Wang X et al. MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36Front Cell Dev Biol.2020 Dec 3;8:596329. WB ; Human.
[IF=2.25] Han, Ying, et al. "Basis of aggravated hepatic lipid metabolism by chronic stress in high-fat diet-fed rat." Endocrine: 1-10. WB ; Rat.
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| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 75 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC27A5: 251-350/690 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SLC27A5 is an isozyme of very long chain acyl CoA synthetase (VLCS). It is an acyl CoA synthetase involved in bile acid metabolism and is proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. It seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, it also activates 3 alpha,7 alpha,12 alpha trihydroxy 5 beta cholestanate (THCA), the C27 precursor of cholic acid derived from the de novo synthesis from cholesterol. Function: Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in liver. Similarity: Belongs to the ATP-dependent AMP-binding enzyme family. SWISS: Q9Y2P5 Gene ID: 10998 Database links: Entrez Gene: 10998 Human Entrez Gene: 26459 Mouse Omim: 603314 Human SwissProt: Q9Y2P5 Human SwissProt: Q4LDG0 Mouse Unigene: 292177 Human Unigene: 10984 Mouse |
