| 產(chǎn)品編號(hào) | bs-3988R |
| 英文名稱 | GLUT5 Rabbit pAb |
| 中文名稱 | 葡萄糖轉(zhuǎn)運(yùn)蛋白5抗體 |
| 別 名 | GLUT-5; GLUT 5; Glucose Transporter 5 GLUT5; Glucose Transporter 5 Facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5 small intestine; SLC2A5; Solute carrier family 2; small intestine. |
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Specific References (3) | bs-3988R has been referenced in 3 publications.
[IF=4.974] Wang,et al.The Transcription Factor AP4 Promotes Oncogenic Phenotypes and Cisplatin Resistance by Regulating LAPTM4B Expression.(2018) Molecular cancer research. 16:857-868. IHC ; Human.
[IF=3.144] Wang,et al.Oat globulin peptides regulate antidiabetic drug targets and glucose transporters in Caco-2 cells.(2018) Journal of Functional Foods. 42:12-20. WB ; Human.
[IF=1.974] Changxin Tian. et al. The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet. ANIM SCI J. 2022 Jan;93(1):e13754 IHC ; Goat.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運(yùn)蛋白 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 55 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GLUT5: 131-180/501 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Ten types of glucose/fructose transport carrier proteins designated as Glut 1-10 facilitate glucose/fructose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45%-65%) all in the molecular weight range of 40-60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. Majority of the differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue-specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers. Glut 5 seems to function primarily as a fructose transporter; it is expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose Function: Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. SWISS: P22732 Gene ID: 6518 Database links: Entrez Gene: 6518 Human Entrez Gene: 56485 Mouse Omim: 138230 Human SwissProt: P22732 Human SwissProt: Q9WV38 Mouse Unigene: 530003 Human Unigene: 260220 Mouse Unigene: 10900 Rat |
