| 產(chǎn)品編號(hào) | bs-3913R |
| 英文名稱 | Rabbit Anti-SLCO2B1 antibody |
| 中文名稱 | 可溶性載質(zhì)轉(zhuǎn)運(yùn)蛋白2B1抗體 |
| 別 名 | Moat 1; Moat1; Multispecific organic anion transporter 1; Multispecific organic anion transporter1; OATP 2B1; OATP B; OATP RP2; OATP2 B1; OATP2B1; OATPB; OATPRP 2; OATPRP2; Organic anion transporter B; Organic anion transporter polypeptide related protein 2; Organic anion transporter polypeptide related protein2; SLC 21A9; SLC2 1A9; SLC21 A9; SLC21A9; SLCO 2B1; SLCO2 B1; SO 2B1; SO2 B1; SO2B1; Solute carrier family 21 (organic anion transporter), member 9; Solute carrier family 21 member 9; Solute carrier organic anion transporter family member 2B1; SO2B1_HUMAN. |
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Specific References (2) | bs-3913R has been referenced in 2 publications.
[IF=10.334] Wenlong Li. et al. Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs. PHARMACOL RES. 2023 Mar;:106724 IHC ; Mouse.
[IF=3.84] Yamamoto, Kotaro, et al. "The neuroprotective effect of latanoprost acts via klotho‐mediated suppression of calpain activation after optic nerve transection." Journal of Neurochemistry (2016). IHC-F ; Rat.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Rabbit,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 77kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLCO2B1: 531-630/709 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SLCO2B1 (solute carrier organic anion transporter family member 2B1), or Organic anion transporter B (OATP-B) mediates sodium-independent transport of organic anions. Unlike other related proteins, SLCO2B1 is expressed in many tissues, including liver, placenta, brain, heart and intestine. SLCO2B1 plays a role in the uptake of steroids and a number of drugs such as statins. Function: Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. SWISS: O94956 Gene ID: 11309 Database links: Entrez Gene: 11309 Human Entrez Gene: 101488 Mouse Omim: 604988 Human SwissProt: O94956 Human SwissProt: Q8BXB6 Mouse Unigene: 7884 Human Unigene: 11249 Mouse Unigene: 44538 Rat OATPRP2又稱陰離子轉(zhuǎn)運(yùn)蛋白家族2B1、有機(jī)陰離子轉(zhuǎn)運(yùn)多肽相關(guān)蛋白2。 |
| 產(chǎn)品圖片 |
Sample:
Cerebrum (Mouse) Lysate at 40 ug
Cerebrum (Rat) Lysate at 40 ug
Primary: Anti- SLCO2B1 (bs-3913R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 77 kD
Observed band size: 87 kD
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-SLCO2B1 Polyclonal Antibody, Unconjugated(bs-3913R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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