| 產(chǎn)品編號 | bs-3598R |
| 英文名稱 | CXCR5 Rabbit pAb |
| 中文名稱 | 細(xì)胞表面趨化因子受體5（CD185）抗體 |
| 別 名 | BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Ch |
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Specific References (3) | bs-3598R has been referenced in 3 publications.
[IF=5.215] Tianrui Zhang. et al. Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization. PHARMACEUTICALS-BASE. 2023 Feb;16(2):243 WB ; Rat.
[IF=3.23] Huang, Hu, et al. "Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice." PloS one 12.3 (2017): e0173716. WB, IHC-F ; Mouse.
[IF=1.26] Gong, Qiaoqiao, et al. "Increased levels of CCR7 (lo) PD?1 (hi) CXCR5+ CD4+ T cells, and associated factors Bcl?6, CXCR5, IL?21 and IL?6 contribute to repeated implantation failure." Experimental and Therapeutic Medicine 14.6 (2017): 5931-5941. IHC-P ; Human.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 趨化因子 G蛋白偶聯(lián)受體 b-淋巴細(xì)胞 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 45 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CXCR5/CD185: 281-372/372 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Function: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expression in mature B-cells and Burkitt lymphoma cells. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P32302 Gene ID: 643 Database links: Entrez Gene: 643 Human Entrez Gene: 12145 Mouse Omim: 601613 Human SwissProt: P32302 Human SwissProt: Q04683 Mouse Unigene: 113916 Human Unigene: 490637 Mouse Unigene: 6246 Mouse Unigene: 120732 Rat Unigene: 127121 Rat |
| 產(chǎn)品圖片 |
Sample:
Raji cell(human) Lysate at 40 ug
Lymph node(mouse)Lysate at 40 ug
Primary: Anti-CXCR5 (bs-3598R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42kD
Observed band size: 42 kD
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