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Motilin Rabbit pAb (bs-1445R)  
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產(chǎn)品編號 bs-1445R
英文名稱 Motilin Rabbit pAb
中文名稱 胃動素抗體
別    名 Motilin; MGC138519; MLN; Motilin-associated peptide; Promotilin; MOTI_HUMAN.  
Specific References  (2)     |     bs-1445R has been referenced in 2 publications.
[IF=10.257] Jiao Ma. et al. A robust composite hydrogel consisting of polypyrrole and β-cyclodextrin-based supramolecular complex for the label-free amperometric immunodetection of motilin with well-defined dual signal response and high sensitivity. Biosens Bioelectron. 2021 Feb;173:112810  Other ;  
[IF=1.52] Liang Q et al. Evaluation of a modified rat model for functional dyspepsia.Saudi J Gastroenterol. 2018 Jul-Aug;24(4):228-235.  IHC-P ;  Rat.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 10.3 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MLN: 51-115/115 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq, Jul 2008]

Function:
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.

Subcellular Location:
Secreted.

Similarity:
Belongs to the motilin family.

SWISS:
P12872

Gene ID:
4295

Database links:

Entrez Gene: 4295 Human

Omim: 158270 Human

SwissProt: P12872 Human

SwissProt: P01307 Pig

SwissProt: P27114 Rabbit

SwissProt: O18845 Sheep

Unigene: 2813 Human



胃動素屬于興奮胃腸道平滑肌運動的腦腸肽,主要在胃腸道表達。
產(chǎn)品圖片
Tissue/cell: Rat stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Motilin Polyclonal Antibody, Unconjugated(bs-1445R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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